Hours Of Operations Rue 21 Wisconsin La Crosse 54601 Rue 21 Hours of Operation and Location in La Crosse, WI 54601 4.2 - 121 votes 3800 State Road 16, #169, La Crosse, WI 54601 (608) 781-4911 Get Directions Rue 21 Hours Category: Apparel Grocery & Market Hours Hours may vary due to season or holiday reasons. For specific hours, please contact store directly. Map Explore La CrosseView More Apparel KmartBig LotsDeb ShopsH & MCarhartt Sports LA FitnessDick's Sporting GoodsVansSnap FitnessZumiez Jewelry Deb ShopsZalesKay JewelersPiercing PagodaRogers Jewelers Recommend For You Centurylink Lush Dick's Sporting Goods Ross Stores Yankee Candle Sleep Number Cosmo Prof ADT Build-A Bear Workshop J. C. Penney