Hours Of Operations Rue 21 Wisconsin La Crosse Rue 21 Hours of Operation and Locations in La Crosse, WI 4.5 - 48 votes 1 Locations in La Crosse rue21.com Rue 21 Hours Category: Apparel Grocery & Market Rue 21 - La Crosse, WI 54601 3800 State Road 16, #169(608) 781-4911 View Store Details Explore La CrosseView More Apparel KmartBig LotsDeb ShopsH & MCarhartt Sports LA FitnessDick's Sporting GoodsVansSnap FitnessZumiez Jewelry Deb ShopsZalesKay JewelersPiercing PagodaRogers Jewelers Recommend For You American Furniture Warehouse Raymour & Flanigan Jo-Ann Fabric and Craft Centurylink Sport Chalet Brandy Melville The Vitamin Shoppe Performance Bicycle The Children's Place Custom Ink