Hours Of Operations Rue 21 South Carolina Bluffton 29910 Rue 21 Hours of Operation and Location in Bluffton, SC 29910 4.3 - 18 votes 1414 Fording Island Rd, #C150, Bluffton, SC 29910 (843) 836-2080 Get Directions Rue 21 Hours Category: Apparel Grocery & Market Hours Hours may vary due to season or holiday reasons. For specific hours, please contact store directly. Map Explore BlufftonView More Apparel MarshallsRoss Dress for LessBig LotsStein MartCarhartt Sports TargetNew BalanceNikeDick's Sporting GoodsSkechers Jewelry MarshallsSaks Fifth AvenueKay JewelersChico'sJ Jill Recommend For You The Children's Place Dick's Sporting Goods Ross Stores New York & Company Grainger Johnston & Murphy At Home Crossfit Deb Ferguson