Hours Of Operations Rue 21 Missouri Sikeston 63801 Rue 21 Hours of Operation and Location in Sikeston, MO 63801 4.2 - 118 votes 100 Outlet Dr # 37, Sikeston, MO 63801 (573) 471-2588 Get Directions Rue 21 Hours Category: Apparel Grocery & Market Hours Hours may vary due to season or holiday reasons. For specific hours, please contact store directly. Map Explore SikestonView More Apparel Goody'sCatoCarharttCarter'sJCPenney Sports ColemanBladesCity GearBasic Basic Jewelry CatoDressbarn Outlet Recommend For You ADT J. C. Penney Deb Ferguson Goodwill Bob's Stores City Gear Hanes Carter's El Toro Market