Hours Of Operations Rue 21 Missouri Hannibal 63401 Rue 21 Hours of Operation and Location in Hannibal, MO 63401 4.5 - 132 votes 210 Huck Finn Shopping Ctr, Hannibal, MO 63401 (573) 231-0700 Get Directions Rue 21 Hours Category: Apparel Grocery & Market Hours Hours may vary due to season or holiday reasons. For specific hours, please contact store directly. Map Explore HannibalView More Apparel Big LotsGoody'sCarharttJCPenneyCatherines Sports VansCross CountryDunham's Sports Recommend For You ADT J. C. Penney At Home Chem-Dry Danner Deb Goodwill Omega El Toro Market A Nails