Hours Of Operations Rue 21 Mississippi Tupelo Rue 21 Hours of Operation and Locations in Tupelo, MS 4.5 - 48 votes 1 Locations in Tupelo rue21.com Rue 21 Hours Category: Apparel Grocery & Market Rue 21 - Tupelo, MS 38804 3850 Market Center Dr(662) 840-4326 View Store Details Explore TupeloView More Apparel Sam's ClubTJ MaxxRoss Dress for LessBig LotsCato Sports Dick's Sporting GoodsVansColemanSnap FitnessFootaction USA Jewelry Sam's ClubHobby LobbyCatoKohl's OutletBelk Recommend For You American Furniture Warehouse Raymour & Flanigan Jo-Ann Fabric and Craft Centurylink Sport Chalet Brandy Melville The Vitamin Shoppe Performance Bicycle The Children's Place Custom Ink