Hours Of Operations Rue 21 Mississippi Philadelphia 39350 Rue 21 Hours of Operation and Location in Philadelphia, MS 39350 4.3 - 77 votes 211 Lewis Ave N, #10, Philadelphia, MS 39350 (601) 663-0629 Get Directions Rue 21 Hours Category: Apparel Grocery & Market Hours Hours may vary due to season or holiday reasons. For specific hours, please contact store directly. Map Explore PhiladelphiaView More Apparel Goody'sCatoPeeblesH & MCarhartt Sports VansColeman Jewelry CatoAvon Recommend For You ADT Deb Ferguson Merle Norman Cosmetic Studio Bob's Stores Bargain Shop Carter's El Toro Market A+ Roofing Deli & Grocery