Hours Of Operations Rue 21 Iowa Spencer 51301 Rue 21 Hours of Operation and Location in Spencer, IA 51301 4.2 - 117 votes 901 11th St Sw, #45, Spencer, IA 51301 (712) 262-0107 Get Directions Rue 21 Hours Category: Apparel Grocery & Market Hours Hours may vary due to season or holiday reasons. For specific hours, please contact store directly. Map Explore SpencerView More Apparel PeeblesCarharttJCPenneyExpressDiesel Sports VansBladesSport's PageDunham's Sports Jewelry Avon Recommend For You J. C. Penney Goodwill I wireless Omega Beltone Hearing Aid Center Slumberland El Toro Market Schweser's A Nails A Salon