Hours Of Operations Lowe's South Carolina Hartsville Lowe's Hours of Operation and Locations in Hartsville, SC 4.6 - 205 votes 1 Locations in Hartsville Lowe's Hours Category: Home & Garden Lowe's - Hartsville, SC 29550 819 South Fourth St(843) 339-2501 View Store Details Explore HartsvilleView More Apparel Big LotsGoody'sCatoH & MCarhartt Sports Sports Time Jewelry CatoBelk Recommend For You High's of Baltimore Krauszer's Food Store Eileen Fisher North Face Quality Mart Dakota Watch Company Glitter Pak-A-Sak Cavender's Madewell