Hours Of Operations Lowe's Home Improvement South Carolina Florence 29501 Lowe's Home Improvement Hours of Operation and Location in Florence, SC 29501 4.0 - 159 votes 2387 David H Mcleod Blvd, Florence, SC 29501 (843) 679-4053 Get Directions Lowe's Home Improvement Hours Category: Home & Garden Hours Hours may vary due to season or holiday reasons. For specific hours, please contact store directly. Map Explore FlorenceView More Apparel Sam's ClubTJ MaxxRoss Dress for LessKmartBig Lots Sports TargetDick's Sporting GoodsColemanAcademy Sports + OutdoorsOnce Upon A Child Jewelry Sam's ClubHobby LobbyCatoZalesKohl's Outlet Recommend For You Quicksilver Resources Incorporated S & A Liquor S & C Food Screen Shop Sears Home Improvements Star Sports Incorporated The Home Depot Installation Services York International New York