Hours Of Operations Home Depot Texas Mesquite Home Depot Hours of Operation and Locations in Mesquite, TX 4.9 - 147 votes 1 Locations in Mesquite Home Depot Hours Category: Home & Garden Home Depot - Mesquite, TX 75150 18855 I-635(972) 682-6294 View Store Details Explore MesquiteView More Apparel MarshallsRoss Dress for LessBurlington Coat FactoryBig LotsK & G Fashion Superstore Sports TargetSheplersVansColemanSnap Fitness Jewelry MarshallsHobby LobbyBurlington Coat FactoryZalesKohl's Outlet Recommend For You CVS Target IKEA Michaels Costco Marshalls Sports Authority Walgreens Publix Great Clips