Hours Of Operations Home Depot New York Williamsville Home Depot Hours of Operation and Locations in Williamsville, NY 4.9 - 147 votes 1 Locations in Williamsville Home Depot Hours Category: Home & Garden Home Depot - Williamsville, NY 14221 4139 Transit Rd(716) 633-9200 View Store Details Explore WilliamsvilleView More Apparel MarshallsTJ MaxxStein MartCarharttKohl's Outlet Sports TargetNikeFinish Line Jewelry MarshallsZalesKohl's OutletTen Thousand VillagesAlex and Ani Recommend For You CVS Target IKEA Michaels Costco Marshalls Sports Authority Walgreens Publix Great Clips