Hours Of Operations Home Depot Missouri Independence Home Depot Hours of Operation and Locations in Independence, MO 4.9 - 147 votes 1 Locations in Independence Home Depot Hours Category: Home & Garden Home Depot - Independence, MO 64055 4210 S Lees Summit Rd(816) 478-3300 View Store Details Explore IndependenceView More Apparel Sam's ClubCostcoMarshallsRoss Dress for LessBurlington Coat Factory Sports CostcoTargetBass Pro ShopsDick's Sporting GoodsColeman Jewelry Sam's ClubCostcoMarshallsHobby LobbyBurlington Coat Factory Recommend For You CVS Target IKEA Michaels Costco Marshalls Sports Authority Walgreens Publix Great Clips