Hours Of Operations Home Depot Missouri Gladstone Home Depot Hours of Operation and Locations in Gladstone, MO 4.9 - 147 votes 1 Locations in Gladstone Home Depot Hours Category: Home & Garden Home Depot - Gladstone, MO 64118 4949 NW Old Pike Rd(816) 459-9950 View Store Details Recommend For You CVS Target IKEA Michaels Costco Marshalls Sports Authority Walgreens Publix Great Clips