Hours Of Operations Home Depot Massachusetts Waltham Home Depot Hours of Operation and Locations in Waltham, MA 4.9 - 147 votes 1 Locations in Waltham Home Depot Hours Category: Home & Garden Home Depot - Waltham, MA 02451 100 1st Ave(781) 672-0900 View Store Details Explore WalthamView More Apparel CostcoTJ MaxxH & MCarter'sCatherines Sports CostcoVansColemanSport CenterTrack Field STORE Jewelry CostcoThe Paper StoreFashion Boutique Recommend For You CVS Target IKEA Michaels Costco Marshalls Sports Authority Walgreens Publix Great Clips