Hours Of Operations Home Depot Kentucky Florence Home Depot Hours of Operation and Locations in Florence, KY 4.9 - 147 votes 1 Locations in Florence Home Depot Hours Category: Home & Garden Home Depot - Florence, KY 41042 99 Spiral Dr(859) 283-1460 View Store Details Explore FlorenceView More Apparel Sam's ClubTJ MaxxBig LotsOllie's Bargain OutletH & M Sports TargetLA FitnessDick's Sporting GoodsSkechersVans Jewelry Sam's ClubHobby LobbyZalesKohl's OutletKay Jewelers Recommend For You CVS Target IKEA Michaels Costco Marshalls Sports Authority Walgreens Publix Great Clips