Hours Of Operations Home Depot Florida Leesburg Home Depot Hours of Operation and Locations in Leesburg, FL 4.9 - 147 votes 1 Locations in Leesburg Home Depot Hours Category: Home & Garden Home Depot - Leesburg, FL 34788 10825 US Highway 441(352) 742-1252 View Store Details Explore LeesburgView More Apparel Big LotsH & MCarharttRooms To GoBealls Sports TargetRural KingVansVitamin WorldDelia's Jewelry ZalesBeallsBelkKay JewelersGold Center Recommend For You CVS Target IKEA Michaels Costco Marshalls Sports Authority Walgreens Publix Great Clips