Hours Of Operations Home Depot California Irvine Home Depot Hours of Operation and Locations in Irvine, CA 4.9 - 147 votes 1 Locations in Irvine Home Depot Hours Category: Home & Garden Home Depot - Irvine, CA 92620 6200 Irvine Blvd(949) 262-0685 View Store Details Explore IrvineView More Apparel CostcoMarshallsTJ MaxxStein MartBrandy Melville Sports CostcoTargetSports AuthorityNew BalanceBig 5 Sporting Goods Jewelry CostcoMarshallsKohl's OutletKay JewelersChico's Recommend For You CVS Target IKEA Michaels Costco Marshalls Sports Authority Walgreens Publix Great Clips