Hours Of Operations CVS Massachusetts Southbridge CVS Hours of Operation and Locations in Southbridge, MA 4.9 - 221 votes 1 Locations in Southbridge CVS Hours Category: Beauty & Health CVS/pharmacy - Southbridge, MA 1550 399 Main St(508) 765-0646 View Store Details Explore SouthbridgeView More Apparel CatherinesTalbotsHurleyLacosteNew York Sports Blades Recommend For You Target IKEA Michaels Costco Marshalls Sports Authority Walgreens Publix Great Clips Sally Beauty Supply